Gobind
Khorana
Protein
Engineering
Core
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Beckman Optima AUC – Analytical Ultracentrifugation
Absolute macromolecular characterization in solution.​
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The Optima AUC uses ultra-high centrifugal forces to analyze proteins, nucleic acids, nanoparticles, and complexes in solution. It measures sedimentation and diffusion in real time via absorbance and/or interference optics, providing molecular weight, shape, aggregation, heterogeneity, and interactions without labeling or immobilization.
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Key Benefits:
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Configurable with absorbance (UV-Vis) and/or interference optics for flexible detection
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Measures sedimentation, diffusion, and molecular weight with high precision
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Multi-wavelength absorbance: up to ~20 discrete wavelengths per experiment
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Ultra-high speed and g-force: up to 60,000 RPM (~290,000 × g)
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Precise temperature control: 4–40 °C for solution-sensitive samples
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